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1 Peter 3:15

But sanctify the Lord Christ in your hearts, being ready always to satisfy every one that asketh you a reason of that hope which is in you.

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The verse in its languages

Vulgate (Clementine)
Dominum autem Christum sanctificate in cordibus vestris, parati semper ad satisfactionem omni poscenti vos rationem de ea, quæ in vobis est, spe.
Greek New Testament (SBLGNT)
κύριον δὲ τὸν Χριστὸν ἁγιάσατε ἐν ταῖς καρδίαις ὑμῶν, ἕτοιμοι ἀεὶ πρὸς ἀπολογίαν παντὶ τῷ αἰτοῦντι ὑμᾶς λόγον περὶ τῆς ἐν ὑμῖν ἐλπίδος,

Haydock's commentary

Always ready to satisfy,1 &c. St. Peter would have every Christian, according to his circumstances and capacity, ready to give general reasons of his faith and hope of salvation, both to infidels and heretics that refuse to believe. (Witham)

1 Ad satisfactionem, pros apologian, ad defensionem.

From Haydock's Catholic Bible Commentary, 1859, in the transcription made by Todd Easton and kept online by John Paul Wohlschied at johnblood.gitlab.io/haydock.

The Fathers on this verse

Clement of Alexandria The Stromata, or Miscellanies, Fragments of Clemens Alexandrinus

“But sanctify the Lord Christ,” he says, “in your hearts.” For so you have in the Lord’s prayer, “Hallowed be Thy name.”

Origen Origen Against Celsus, Chapter XXXIII

Celsus, however, shows that he has read a good many Grecian histories, when he quotes further what is told of Cleomedes of Astypalæa, “who,” he relates, “entered into an ark, and although shut up within it, was not found therein, but through some arrangement of the divinity, flew out, when certain persons had cut open the ark in order to apprehend him.” Now this story, if an invention, as it appears to be, cannot be compared with what is related of Jesus, since in the lives of such men there is found no indication of their possessing the divinity which is ascribed to them; whereas the divinity of Jesus is established both by the existence of the Churches of the saved, and by the prophecies uttered concerning Him, and by the cures wrought in His name, and by the wisdom and knowledge which are in Him, and the deeper truths which are discovered by those who know how to ascend from a simple …

Origen Origen Against Celsus, Chapter XII

He thinks, besides, that those who support the cause of Christ by a reference to the writings of the prophets can give no proper answer in regard to statements in them which attribute to God that which is wicked, shameful, or impure; and assuming that no answer can be given, he proceeds to draw a whole train of inferences, none of which can be allowed. But he ought to know that those who wish to live according to the teaching of sacred Scripture understand the saying, “The knowledge of the unwise is as talk without sense,” and have learnt “to be ready always to give an answer to every one that asketh us a reason for the hope that is in us.” And they are not satisfied with affirming that such and such things have been predicted; but they endeavour to remove any apparent inconsistencies, and to show that, so far from there being anything evil, shameful, or impure in these predictions, ever …

St Augustine Answer to the Letters of Petilian, the Donatist, Chapter 19

43. Augustin answered: To flee from one state to another from the face of persecution has not been enjoined as precept or permission on heretics or schismatics, such as you are; but it was enjoined on the preachers of the gospel, whom you resist. And this we may easily prove in this wise: you are now in your own cities, and no man persecutes you. You must therefore come forth, and give an account of your separation. For it cannot be maintained that, as the weakness of the flesh is excused when it yields before the violence of persecution, so truth also ought to yield to falsehood. …

St John Chrysostom Treatise Concerning the Christian Priesthood, Book IV

8. Hear also what he says in his charge to his disciple: “Give heed to reading, to exhortation, to teaching,” and he goes on to show the usefulness of this by adding, “For in doing this thou shalt save both thyself and them that hear thee.” And again he says, “The Lord’s servant must not strive, but be gentle towards all, apt to teach, forbearing;” and he proceeds to say, “But abide thou in the things which thou hast learned, and hast been assured of, knowing of whom thou hast learned them, and that from a babe thou hast known the sacred writings which are able to make thee wise unto salvation,” and again, “Every Scripture is inspired of God, and also profitable for teaching, for reproof, for correction, for instruction which is in righteousness, that the man of God may be complete.” Hear what he adds further in his directions to Titus about the appointment of bishops. …

St John Chrysostom The Homilies of St. John Chrysostom, Matthew X. 16

For this cause then, though He said, “Take no thought what ye shall speak;” yet elsewhere He saith, “Be ready to give an answer to every man that asketh you a reason of the hope that is in you.” That is, as long as the contest is among friends, He commands us also to take thought; but when there is a terrible tribunal, and frantic assemblies, and terrors on all sides, He bestows the influence from Himself, that they may take courage and speak out, and not be discouraged, nor betray the righteous cause.

St John Chrysostom Homilies on First Corinthians, Homily III

Wherefore, lest we fall into the same error, and be laughed to scorn, arguing thus with Greeks whenever we have a controversy with them; let us charge the Apostles with want of learning; for this same charge is praise. And when they say that the Apostles were rude, let us follow up the remark and say that they were also untaught, and unlettered, and poor, and vile, and stupid, and obscure. It is not a slander on the Apostles to say so, but it is even a glory that, being such, they should have outshone the whole world. For these untrained, and rude, and illiterate men, as completely vanquished the wise, and powerful, and the tyrants, and those who flourished in wealth and glory and all outward good things, as though they had not been men at all: from whence it is manifest that great is the power of the Cross; and that these things were done by no human strength. …

St John Chrysostom The Homilies of St. John Chrysostom on the Gospel of St. John, John 1.28,29

Must not this deserve excessive wrath, when Christ is shown to be less honorable in your estimation than a dancer? since you have contrived ten thousand defenses for the things they have done, though more disgraceful than any, but of the miracles of Christ, though they have drawn to Him the world, you cannot bear even to think or care at all. We believe in the Father, and the Son, and the Holy Ghost, in the Resurrection of bodies, and in Life everlasting. …

Theodoret Dialogues. The “Eranistes” or “Polymorphus” of the Blessed Theodoretus, Bishop of Cyrus, The Unconfounded

Orth. Why not then teach the faithful the reality of the doctrine? Are you forgetful of the apostolic precept enjoining us to be “ready to give an answer.” Now let us look at the matter in this light. Does the best general engage the enemy, attack with arrows and javelins, and endeavour to break their column all alone, or does he also arm his men, and marshal them, and rouse their hearts to play the man?

Rufinus A Commentary on the Apostles' Creed, Section 28

28. That He descended into hell is also evidently foretold in the Psalms, where it is said, “Thou hast brought Me also into the dust of the death.” And again, “What profit is there in my blood, when I shall have descended into corruption?” And again, “I descended into the deep mire, where there is no bottom.” Moreover, John says, “Art Thou He that shall come (into hell, without doubt), or do we look for another?” Whence also Peter says that “Christ being put to death in the flesh, but quickened in the Spirit which dwells in Him, descended to the spirits who were shut up in prison, who in the days of Noah believed not, to preach unto them;” where also what He did in hell is declared. …

St Jerome The Letters of St. Jerome, To Nepotian

7. Read the divine scriptures constantly; never, indeed, let the sacred volume be out of your hand. Learn what you have to teach. “Hold fast the faithful word as you have been taught that you may be able by sound doctrine to exhort and convince the gainsayers. Continue thou in the things that thou hast learned and hast been assured of, knowing of whom thou hast learned them;” and “be ready always to give an answer to every man that asketh you a reason of the hope and faith that are in you.” Do not let your deeds belie your words; lest when you speak in church someone may mentally reply “Why do you not practise what you profess? Here is a lover of dainties turned censor! his stomach is full and he reads us a homily on fasting. As well might a robber accuse others of covetousness.” In a priest of Christ mouth, mind, and hand should be at one.

St Jerome To Pammachius against John of Jerusalem

4. And first, before I translate and insert in this book the letter which you wrote to Bishop Theophilus, and show you that I understand your excessive care and circumspection, I should like a word of expostulation with you. What is the meaning of this towering arrogance which makes you refuse to reply to those who question you respecting the faith? How is it that you regard almost as public enemies the vast multitude of brethren, and the bands of monks, who refuse to communicate with you in Palestine? The Son of God, for the sake of one sick sheep, leaving the ninety and nine on the mountains, endured the buffeting, the cross, the scourge; He took up the burden, and patiently carried on His shoulders to heaven the voluptuous woman that was a sinner. …

2 more passages of the Fathers cite this verse. The Motif Searcher in the palace lists them all.