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1 Timothy 2:8

I will therefore that men pray in every place, lifting up pure hands, without anger and contention.

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The verse in its languages

Vulgate (Clementine)
Volo ergo viros orare in omni loco, levantes puras manus sine ira et disceptatione.
Greek New Testament (SBLGNT)
Βούλομαι οὖν προσεύχεσθαι τοὺς ἄνδρας ἐν παντὶ τόπῳ, ἐπαίροντας ὁσίους χεῖρας χωρὶς ὀργῆς καὶ διαλογισμοῦ.

Haydock's commentary

How beautifully does St. Paul teach that modesty and chastity are the greatest ornaments of the female sex, not only in the sight of God and of Angels, but also of men, who although by their own neglect they have not always grace and courage sufficient to be virtuous themselves, cannot help admiring virtue wherever they see it in others. Even the pagan fully acknowledges the native attractions of virtue. Virtus per se placet: Virtue pleases with unborrowed charms.

From Haydock's Catholic Bible Commentary, 1859, in the transcription made by Todd Easton and kept online by John Paul Wohlschied at johnblood.gitlab.io/haydock.

The Fathers on this verse

Tertullian On Prayer, Of Washing the Hands

But what reason is there in going to prayer with hands indeed washed, but the spirit foul? inasmuch as to our hands themselves spiritual purities are necessary, that they may be “lifted up pure” from falsehood, from murder, from cruelty, from poisonings, from idolatry, and all the other blemishes which, conceived by the spirit, are effected by the operation of the hands. These are the true purities; not those which most are superstitiously careful about, taking water at every prayer, even when they are coming from a bath of the whole body. When I was scrupulously making a thorough investigation of this practice, and searching into the reason of it, I ascertained it to be a commemorative act, bearing on the surrender of our Lord. …

Tertullian On Prayer, Of Kneeling

In the matter of kneeling also prayer is subject to diversity of observance, through the act of some few who abstain from kneeling on the Sabbath; and since this dissension is particularly on its trial before the churches, the Lord will give His grace that the dissentients may either yield, or else indulge their opinion without offence to others. We, however (just as we have received), only on the day of the Lord’s Resurrection ought to guard not only against kneeling, but every posture and office of solicitude; deferring even our businesses lest we give any place to the devil. Similarly, too, in the period of Pentecost; which period we distinguish by the same solemnity of exultation. …

St Augustine Expositions on the Book of Psalms, Psalm LXIII

10. “So I will speak good of Thee in my life, and in Thy name I will lift up my hands” ( ver. 5 ). Now in my life which to me Thou hast given, not in that which I have chosen after the world with the rest among many lives, but that which Thou hast given to me through Thy mercy, that I should praise Thee. “So I will speak good of Thee in my life.” What is “so”? That to Thy mercy I may ascribe my life wherein Thee I praise, not to my merits. “And in Thy name I will lift up my hands.” Lift up therefore hands in prayer. Our Lord hath lifted up for us His hands on the Cross, and stretched out were His hands for us, and therefore were His hands stretched out on the Cross, in order that our hands might be stretched out unto good works: because His Cross hath brought us mercy. …

St John Chrysostom The Homilies of St. John Chrysostom, Matthew XV. 1

For so Paul too commanded: his phrase being, “lifting up holy hands without wrath and disputing.” Dishonor not then thy tongue, for how will it entreat for thee, when it hath lost its proper confidence? but adorn it with gentleness, with humility, make it worthy of the God who is entreated, fill it with blessing, with much almsdoing. For it is possible even with words to do alms. “For a word is a better thing than a gift,”and “answer the poor man peaceably with meekness.” And all the rest of thy time too adorn it with the rehearsing of the laws of God; “Yea, let all thy communication be in the law of the Most High.”

St John Chrysostom A Commentary on the Acts of the Apostles, Homily XVII on Acts vii. 35

Such is the boldness of speech of a man bearing the Cross. Let us then also imitate this: though it be not a time of war, yet it is always the time for boldness of speech. For, “I spake,” says one, “in Thy testimonies before kings, and was not ashamed.” ( Ps. cxix. 46 .) If we chance to be among heathens, let us thus stop their mouths. without wrath, without harshness. (Comp. Hom. in 1 Cor. iv. §6; xxxiii. §4, 5; Col. xi. §2.) For if we do it with wrath, it no longer seems to be the boldness (of one who is confident of his cause,) but passion: but if with gentleness, this is boldness indeed. For in one and the same thing success and failure cannot possibly go together. The boldness is a success: the anger is a failure. Therefore, if we are to have boldness, we must be clean from wrath that none may impute our words to that. …

St John Chrysostom The Homilies of St. John Chrysostom on Timothy, Titus, and Philemon, 1 Timothy 2:8-10

1 Timothy ii. 8-10 “I will therefore that men pray everywhere, lifting up holy hands, without wrath and doubting. In like manner also, that women adorn themselves in modest apparel, with shamefacedness and sobriety; not with broidered hair, or gold, or pearls, or costly array; but (which becometh women professing godliness) with good works.”

St Jerome Against Jovinianus, Book I

27. But we toil to no purpose. For our opponent urges against us the Apostolic sentence and says, “Adam was first formed, then Eve; and Adam was not beguiled, but the woman being beguiled hath fallen into transgression: but she shall be saved through the child-bearing, if they continue in faith and love and sanctification with sobriety.” Let us consider what led the Apostle to make this declaration:“I desire therefore that the men pray in every place, lifting up holy hands, without wrath and disputing.” So in due course he lays down rules of life for the women and says “In like manner that women adorn themselves in modest apparel, with shamefacedness and sobriety; not with braided hair, and gold or pearls or costly raiment; but (which becometh women professing godliness) through good works. Let a woman learn in quietness with all subjection. …

St Gregory Nazianzen The Oration on Holy Baptism

XXXIX. And in addition to what has been said, it is good with our head cleansed, as the head which is the workshop of the senses is cleansed, to hold fast the Head of Christ, from which the whole body is fitly joined together and compacted; and to cast down our sin that exalted itself, when it would exalt us above our better part. It is good also for the shoulder to be sanctified and purified that it may be able to take up the Cross of Christ, which not everyone can easily do. …

St John Cassian The Twelve Books on the Institutes of the Cœnobia, and the Remedies for the Eight Principal Faults, Chapter XIII. That we should not retain our anger even for an instant

Or how can we think that the Lord would have it retained even for an instant, since He does not permit us to offer the spiritual sacrifices of our prayers, if we are aware that another has any bitterness against us: saying, “If then thou bringest thy gift to the altar and there rememberest that thy brother hath aught against thee, leave there thy gift at the altar and go thy way; first be reconciled to thy brother, and then come and offer thy gift.” How then may we retain displeasure against our brother, I will not say for several days, but even till the going down of the sun, if we are not allowed to offer our prayers to God while he has anything against us? And yet we are commanded by the Apostle: “Pray without ceasing;” and “in every place lifting up holy hands without wrath and disputing.” It remains then either that we never pray at all, retaining this poison in our hearts, and beco …

St John Cassian The Conferences of John Cassian. Part I. Containing Conferences I-X, Chapter III. How pure and sincere prayer can be gained

And therefore in order that prayer may be offered up with that earnestness and purity with which it ought to be, we must by all means observe these rules. First all anxiety about carnal things must be entirely got rid of; next we must leave no room for not merely the care but even the recollection of any business affairs, and in like manner also must lay aside all backbitings, vain and incessant chattering, and buffoonery; anger above all and disturbing moroseness must be entirely destroyed, and the deadly taint of carnal lust and covetousness be torn up by the roots. …

St John Cassian The Conferences of John Cassian. Part I. Containing Conferences I-X, Chapter VI. Of the vision which a certain Elder saw concerning the restless work of a brother

And that this is not done without the prompting of devils we are taught by the surest proofs, for when one very highly esteemed Elder was passing by the cell of a certain brother who was suffering from this mental disease of which we have spoken, as he was restlessly toiling in his daily occupations in building and repairing what was unnecessary, he watched him from a distance breaking a very hard stone with a heavy hammer, and saw a certain Ethiopian standing over him and together with him striking the blows of the hammer with joined and clasped hands, and urging him on with fiery incitements to diligence in the work: and so he stood still for a long while in astonishment at the force of the fierce demon and the deceitfulness of such an illusion. …

The Catechism cites this verse