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1 Timothy 3:2

It behoveth therefore a bishop to be blameless, the husband of one wife, sober, prudent, of good behaviour, chaste, given to hospitality, a teacher,

Challoner: Of one wifeThe meaning is not that every bishop should have a wife (for St. Paul himself had none), but that no one should be admitted to the holy orders of bishop, priest, or deacon, who had been married more than once.
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The verse in its languages

Vulgate (Clementine)
Oportet ergo episcopum irreprehensibilem esse, unius uxoris virum, sobrium, prudentem, ornatum, pudicum, hospitalem, doctorem,
Greek New Testament (SBLGNT)
δεῖ οὖν τὸν ἐπίσκοπον ἀνεπίλημπτον εἶναι, μιᾶς γυναικὸς ἄνδρα, νηφάλιον, σώφρονα, κόσμιον, φιλόξενον, διδακτικόν,

Haydock's commentary

A bishop (the same name then comprehended priest) to be blameless, as to life and conversation, adorned, (says St. Chrysostom) with all virtues. See also St. Jerome in his letter to Oceanus.

The1 husband of one wife. It does not signify, that to be a bishop or priest he must be a married man; nor that he must be a man who has but one wife at a time; but that he must be a man who has never been married but once, or to one wife: because to be married more than once, was looked upon as a mark of too great an inclination to sensual pleasures. It is true, at that time a man might be chosen to be a bishop or priest whose wife was living, but from that time he was to live with her as with a sister. This St. Jerome testifies as to the discipline of the Latin Church. (Witham)

The meaning is not that every bishop should have a wife, (for St. Paul himself had none) but that no one should be admitted to the holy orders of bishop, priest, or deacon, who had been married more than once. (Challoner)

Sober.2 The Greek rather signifies watchful.

Chaste.3 There is nothing for this in the Greek text at present, unless in some few manuscripts. Perhaps the ancient Latin interpreter added it, as being signified and comprehended in the other words.

Teacher: a doctor, as the Greek signifies. (Witham)

1 Unius uxoris virum, i.e. non bigamum. See St. Chrysostom, p. 285.

2 Sobrium, nephalion. Vigilantem.

3 Pudicum: some Greek manuscripts, semnon.

From Haydock's Catholic Bible Commentary, 1859, in the transcription made by Todd Easton and kept online by John Paul Wohlschied at johnblood.gitlab.io/haydock.

The Fathers on this verse

Clement of Alexandria The Stromata, or Miscellanies, Book III

Justitiam ergo et salutis harmoniam, quæ est veneranda firmaque, alii quidem, ut ostendimus, nimium intenderunt, blaspheme ac maledice cure quavis impietate suscipientes continentiam; cure pie liceret castitatem, qu secundum sanam regulam instituitur, eligere; gratias quidem agendo propter datam ipsis gratiam, non habendo antem odio creatumm, neque eos aspernando, qui juncti sunt matrimonio; est enim creatus mundus, cream est etiam castitas; ambo autem agant gratias in iis, in quibus sunt collocati, si modo ea quoque norunt, in quibus sunt collocati. …

Tertullian On Monogamy, Chapter XII

Come, now, you who think that an exceptional law of monogamy is made with reference to bishops, abandon withal your remaining disciplinary titles, which, together with monogamy, are ascribed to bishops. Refuse to be “irreprehensible, sober, of good morals, orderly, hospitable, easy to be taught;” nay, indeed, (be) “given to wine, prompt with the hand to strike, combative, money-loving, not ruling your house, nor caring for your children’s discipline,”, no, nor “courting good renown even from strangers.” For if bishops have a law of their own teaching monogamy, the other (characteristics) likewise, which will be the fitting concomitants of monogamy, will have been written (exclusively) for bishops. With laics, however, to whom monogamy is not suitable, the other (characteristics) also have nothing to do. …

The Apostolic Constitutions Book II. Of Bishops, Presbyters, and Deacons, Sec. I. On Examining Candidates for the Episcopal Office

II . Let him therefore be sober, prudent, decent, firm, stable, not given to wine; no striker, but gentle; not a brawler, not covetous; “not a novice, lest, being puffed up with pride, he fall into condemnation, and the snare of the devil: for every one that exalteth himself shall be abased.” Such a one a bishop ought to be, who has been the “husband of one wife,” who also has herself had no other husband, “ruling well his own house.” In this manner let examination be made when he is to receive ordination, and to be placed in his bishopric, whether he be grave, faithful, decent; whether he hath a grave and faithful wife, or has formerly had such a one; whether he hath educated his children piously, and has “brought them up in the nurture and admonition of the Lord;” whether his domestics do fear and reverence him, and are all obedient to him: for if those who are immediately about him fo …

The Apostolic Constitutions Book VI, Sec. III. The Heresies Attacked by the Apostles

XVII. We have already said, that a bishop, a presbyter, and a deacon, when they are constituted, must be but once married, whether their wives be alive or whether they be dead; and that it is not lawful for them, if they are unmarried when they are ordained, to be married afterwards; or if they be then married, to marry a second time, but to be content with that wife which they had when they came to ordination. We also appoint that the ministers, and singers, and readers, and porters, shall be only once married. But if they entered into the clergy before they were married, we permit them to marry, if they have an inclination thereto, lest they sin and incur punishment. But we do not permit any one of the clergy to take to wife either a courtesan, or a servant, or a widow, or one that is divorced, as also the law says. …

Origen Origen's Commentary on Matthew, Chapter XXII

But, while dealing with the passage, I would say that we will be able perhaps now to understand and clearly set forth a question which is hard to grasp and see into, with regard to the legislation of the Apostle concerning ecclesiastical matters; for Paul wishes no one of those of the church, who has attained to any eminence beyond the many, as is attained in the administration of the sacraments, to make trial of a second marriage. For laying down the law in regard to bishops in the first Epistle to Timothy, he says, “If a man seeketh the office of a bishop, he desireth a good work. The bishop, therefore, must be without reproach, the husbands of one wife, temperate, sober-minded,” etc.; and, in regard to deacons, “Let the deacons,” he says, “be the husbands of one wife, ruling their children and their own houses well,” etc. …

St Augustine On the Good of Marriage, Section 21

21. But since out of many souls there shall be hereafter one City of such as have one soul and one heart towards God; which perfection of our unity shall be hereafter, after this sojourn in a strange land, wherein the thoughts of all shall neither be hidden one from another, nor shall be in any matter opposed one to another; on this account the Sacrament of marriage of our time hath been so reduced to one man and one wife, as that it is not lawful to ordain any as a steward of the Church, save the husband of one wife. And this they have understood more acutely who have been of opinion, that neither is he to be ordained, who as a catechumen or as a heathen had a second wife. For it is a matter of sacrament, not of sin. For in baptism all sins are put away. …

St John Chrysostom A Commentary on the Acts of the Apostles, Homily III on Acts i. 12

Let us then also imitate them. And now I address no longer every one, but those who aim at preferment. If thou believest that the election is with God, be not displeased. ( Mark x. 14 , 21 ; xiv. 4 .) For it is with Him thou art displeased, and with Him thou art exasperated: it is He who has made the choice; thou doest the very thing that Cain did; because, forsooth, his brother’s sacrifice was preferred, he was indignant, when he ought to have felt compunction. However, that is not what I mean here; but this, that God knows how to dispense things for the best. In many cases, thou art in point of disposition more estimable than the other but not the fit person. Besides, on the other hand, thy life is irreproachable, and thy habits those of a well-nurtured man, but in the Church this is not all that is wanted. Moreover, one man is adapted for one thing, another for another. …

St John Chrysostom The Homilies of St. John Chrysostom on Timothy, Titus, and Philemon, Argument

2. If it should be asked why he addresses Epistles to Titus and Timothy alone, though Silas was approved, as also was Luke, for he writes, “Only Luke is with me” ( 2 Tim. iv. 11 .), and Clement was one of his associates, of whom he says, “with Clement and other my fellow-laborers” ( Philip. iv. 3 .), for what reason then does he write only to Titus and Timothy? It is because he had already committed the care of churches to these, and certain marked places had been assigned to them, but the others were in attendance upon him. For so preëminent in virtue was Timothy, that his youth was no impediment to his promotion; therefore he writes, “Let no man despise thy youth” ( 1 Tim. iv. 12, and v. 2 .); and again, “The younger women as sisters.” For where there is virtue, all other things are superfluous, and there can be no impediment. …

St John Chrysostom The Homilies of St. John Chrysostom on Timothy, Titus, and Philemon, 1 Timothy 3:1-4

1 Timothy iii. 1-4 “If a man desire the office of a Bishop, he desireth a good work. A Bishop then must be blameless, the husband of one wife, vigilant, sober, of good behavior, given to hospitality, apt to teach; not given to wine, no striker, not greedy of filthy lucre; but patient, not a brawler, not covetous; one that ruleth well his own house, having his children in subjection with all gravity.”

St Athanasius Arian History. (Historia Arianorum ad Monachos.), Arian Persecution Under Constantine

And hence also you may discern its character, and be able to condemn it more confidently. The man who is their friend and their associate in impiety, although he is open to ten thousand charges for other enormities which he has committed; although the evidence and proof against him are most clear; he is approved of by them, and straightway becomes the friend of the Emperor, obtaining an introduction by his impiety; and making very many pretences, he acquires confidence before the magistrates to do whatever he desires. …

St Athanasius Arian History. (Historia Arianorum ad Monachos.), Arian Persecution Under Constantine

In this manner the impious are now proceeding, as heretofore, against the orthodox; giving proof of their malice and impiety amongst all men everywhere. For granting that they have accused Athanasius; yet what have the other Bishops done? On what grounds can they charge them? Has there been found in their case too the dead body of an Arsenius? Is there a Presbyter Macarius, or has a cup been broken amongst them? Is there a Meletian to play the hypocrite? No: but as their proceedings against the other Bishops shew the charges which they have brought against Athanasius, in all probability, to be false; so their attacks upon Athanasius make it plain, that their accusations of the other Bishops are unfounded likewise. …

St Gregory of Nyssa Letters, To the Church at Nicomedia

For it is not lawful that the simple should meddle with that with which they have no concern, but which properly belongs to others. For you should each mind your own business, that so that which is most expedient may come about [and that your Church may again prosper], when those who have been dispersed have returned again to the unit of the one body, and spiritual peace is established by those who devoutly glorify God. To this end it is well, I think, to look out for high qualifications in your election, that he who is appointed to the Presidency may be suitable for the post. …

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The Catechism cites this verse