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Acts 22:21

And he said to me: Go, for unto the Gentiles afar off, will I send thee.

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The verse in its languages

Vulgate (Clementine)
Et dixit ad me : Vade, quoniam ego in nationes longe mittam te.
Greek New Testament (SBLGNT)
καὶ εἶπεν πρός με· Πορεύου, ὅτι ἐγὼ εἰς ἔθνη μακρὰν ἐξαποστελῶ σε.

Haydock's commentary

Hence we see that not only principals, but all that consent to the persecution of God's servants for the cause of religion, do highly offend; and this St. Paul mentions here, that the mercy of God may be more remarkably glorified in him hereby. (Bristow)

From Haydock's Catholic Bible Commentary, 1859, in the transcription made by Todd Easton and kept online by John Paul Wohlschied at johnblood.gitlab.io/haydock.

The Fathers on this verse

St John Chrysostom A Commentary on the Acts of the Apostles, Homily XXI on Acts ix. 26, 27

One may well be much at a loss here to understand how it is that, whereas in the Epistle to the Galatians Paul says, “I went not to Jerusalem,” but “into Arabia” and “to Damascus,” and, “After three years I went up to Jerusalem,” and “to see Peter” ( Gal. i. 17 ), ( ἱστορἥσαι Cat.) here the writer says the contrary. (There, Paul says) “And none of the Apostles saw I; but here, it is said (Barnabas), brought him to the Apostles.”, Well, then, either (Paul) means, “I went not up with intent to refer or attach myself to them ( ἀναθέσθαι ), for what saith he? “I referred not myself, neither went I to Jerusalem to those who were Apostles before me:” or else, that the laying await for him in Damascus was after his return from Arabia; or else, again, that the visit to Jerusalem was after he came from Arabia. …

St John Chrysostom A Commentary on the Acts of the Apostles, Homily XLVIII on Acts xxii. 17-20

See how he thrusts himself (into danger), I came, he says, after that vision, “to Jerusalem. I was in a trance,” etc. Again, this is without witness: but observe, the witness follows from the result. He said, “They will not receive thy testimony:” they did not receive it. And yet from calculations of reason the surmise should have been this, that they would assuredly receive him. For I was the man that made war upon the Christians: so that they ought to have received him. Here he establishes two things: both that they are without excuse, since they persecuted him contrary to all likelihood or calculation of reason; and, that Christ was God, as prophesying things contrary to expectation, and as not looking to past things, but fore-knowing the things to come. How then does He say, “He shall bear My name before the Gentiles and kings and children of Israel?” ( Acts ix. …

St John Chrysostom The Commentary and Homilies of St. John Chrysostom on Galatians and Ephesians, Ephesians 2:17-22

By “dispensation of grace,” he means the revelation made to him. As much as to say, “I learned it not from man. ( Gal. i. 12 .) He vouchsafed to reveal it even to me, though but an individual for your sakes. For Himself said unto me, saith he, “Depart, for I will send thee forth far hence unto the Gentiles.” ( Acts xxii. 21 .) “If so be that ye have heard” for a dispensation it was, a mighty one; to call one, uninfluenced from any other quarter, immediately from above, and to say, “Saul, Saul, why persecutest thou Me?” and to strike him blind with that ineffable light! “if so be that ye have heard,” saith he, “of the dispensation of that grace of God which was given me to you-ward.”

St John Chrysostom The Homilies of St. John Chrysostom on Timothy, Titus, and Philemon, 1 Timothy 1:1,2

1. Great and admirable is the dignity of an Apostle, and we find Paul constantly setting forth the causes of it, not as if he took the honor to himself, but as intrusted with it, and being under the necessity of so doing. For when he speaks of himself as “called,” and that “by the will of God,” and again elsewhere, “a necessity is laid upon me” ( 1 Cor. ix. 16 .), and when he says, “for this I was separated,” by these expressions all idea of arrogance and ambition is removed. For as he deserves the severest blame, who intrudes into an office which is not given him of God, so he who refuses, and shrinks from it when offered to him, incurs blame of another kind, that of rebellion and disobedience. …

St John Chrysostom The Homilies of St. John Chrysostom on the Epistle to the Hebrews, Argument

[1.] The blessed Paul, writing to the Romans, says, “Inasmuch then as I am the Apostle of the Gentiles, I magnify mine office: if by any means I may provoke to emulation them that are my flesh”: and again, in another place, “For He that wrought effectually in Peter to the apostleship of the circumcision, the same was mighty in me toward the Gentiles.” If therefore he were the Apostle of the Gentiles, (for also in the Acts, God said to him, “Depart; for I will send thee far hence unto the Gentiles,”) what had he to do with the Hebrews? and why did he also write an Epistle to them?

St John Chrysostom The Homilies of St. John Chrysostom on the Epistle to the Hebrews, Argument

Why therefore, one might ask, as he was so learned in the law (for he was instructed in the law at the feet of Gamaliel, and had great zeal in the matter, and was especially able to confound them in this respect), why did not God send him to the Jews? Because on this very account they were more vehement in their enmity against him. “For they will not endure thee,” God says unto him; “But depart far hence to the Gentiles, for they will not receive thy testimony concerning me.” Whereupon he says, “Yea, Lord, they know that I imprisoned and beat in every synagogue them that believed on thee; and when the blood of thy martyr Stephen was shed, I also was standing by and consenting unto his death, and kept the raiment of them that slew him.”

The Fathers are given as they wrote. Where a passage lays the Passion on the Jewish people, the Church teaches that it cannot be charged against all the Jews then living, nor against the Jews of today, and that all sinners were its authors (CCC 597, 598).