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Isaias 8:22

And they shall look to the earth, and behold trouble and darkness, weakness and distress, and a mist following them, and they cannot fly away from their distress.

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The verse in its languages

Vulgate (Clementine)
et ad terram intuebitur ; et ecce tribulatio et tenebræ, dissolutio et angustia, et caligo persequens, et non poterit avolare de angustia sua.
Septuagint (Swete)
καὶ εἰς τὴν γῆν κάτω ἐμβλέψονται· καὶ ἰδοὺ ἀπορία στενὴ καὶ σκότος, θλίψις καὶ στενοχωρία καὶ σκότος ὥστε μὴ βλέπειν, καὶ οὐκ ἀπορηθήσεται ὁ ἐν στενοχωρίᾳ ὢν ἕως καιροῦ.
Hebrew (WLC)
וְאֶל אֶ֖רֶץ יַבִּ֑יט וְהִנֵּ֨ה צָרָ֤ה וַחֲשֵׁכָה֙ מְע֣וּף צוּקָ֔ה וַאֲפֵלָ֖ה מְנֻדָּֽח

The Fathers on this verse

St Irenaeus Fragments from the Lost Writings of, XVII

By these Christ was typified, and acknowledged, and brought into the world; for He was prefigured in Joseph: then from Levi and Judah He was descended according to the flesh, as King and Priest; and He was acknowledged by Simeon in the temple: through Zebulon He was believed in among the Gentiles, as says the prophet, “the land of Zabulon;” and through Benjamin [that is, Paul] He was glorified, by being preached throughout all the world.

St Cyprian Three Books of Testimonies Against the Jews, Testimony XXI

In Genesis: “And the Lord God said unto Abraham, Go out from thy country, and from thy kindred, and from thy father’s house, and go into that land which I shall show thee: and I will make of thee a great nation, and I will bless thee, and I will magnify thy name; and thou shalt be blessed: and I will bless him that blesseth thee, and I will curse him that curseth thee: and in thee shall all the tribes of the earth be blessed.” On this same point in Genesis: “And Isaac blessed Jacob. …

St John Chrysostom The Homilies of St. John Chrysostom, Matthew IV. 12

1. Wherefore doth He depart? Again instructing us not to go to meet temptations,but to give place and withdraw ourselves. For it is no reproach, the not casting one’s self into danger, but the failing to stand manfully when fallen into it. To teach us this accordingly, and to soothe the envy of the Jews, He retires to Capernaum; at once fulfilling the prophecy,and making haste to catch the teachers of the world: for they, as you know, were abiding there, following their craft.

St John Chrysostom The Homilies of St. John Chrysostom, Matthew IV. 12

But mark, I pray thee, how in every case when He is about to depart unto the Gentiles, He hath the occasion given Him by Jews. For so in this instance, by plotting against His forerunner, and casting him into prison, they thrust out Christ into the Galilee of the Gentiles. For to show that He neither speaks of the Jewish nation by a part of it, nor signifies obscurely all the tribes; mark how the Prophet distinguishes that place, saying “The land of Nephthalim, by the way of the sea,beyond Jordan, Galilee of the Gentiles, the people which sat in darkness, saw great light:”by darkness here not meaning that which is sensible, but men’s errors and ungodliness. …

St Gregory Nazianzen On the Words of the Gospel, 'When Jesus Had Finished These Sayings,' Etc.--S. Matt. xix. 1

II. Therefore now also, when He had finished these sayings He departed from Galilee and came into the coasts of Judea beyond Jordan; He dwelleth well in Galilee, in order that the people which sat in darkness may see great Light. He removeth to Judea in order that He may persuade people to rise up from the Letter and to follow the Spirit. He teacheth, now on a mountain; now He discourseth on a plain; now He passeth over into a ship; now He rebuketh the surges. And perhaps He goes to sleep, in order that He may bless sleep also; perhaps He is tired that He may hallow weariness also; perhaps He weeps that He may make tears blessed. He removeth from place to place, Who is not contained in any place; the timeless, the bodiless, the uncircumscript, the same Who was and is; Who was both above time, and came under time, and was invisible and is seen. …

The Fathers are given as they wrote. Where a passage lays the Passion on the Jewish people, the Church teaches that it cannot be charged against all the Jews then living, nor against the Jews of today, and that all sinners were its authors (CCC 597, 598).