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Romans 1:4

Who was predestinated the Son of God in power, according to the spirit of sanctification, by the resurrection of our Lord Jesus Christ from the dead;

Challoner: PredestinatedChrist as man, was predestinated to be the Son of God: and declared to be so (as the apostle here signifies) first, by power, that is, by his working stupendous miracles; secondly, by the spirit of sanctification, that is, by his infinite sanctity; thirdly, by his resurrection, or raising himself from the dead.
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The verse in its languages

Vulgate (Clementine)
qui prædestinatus est Filius Dei in virtute secundum spiritum sanctificationis ex resurrectione mortuorum Jesu Christi Domini nostri :
Greek New Testament (SBLGNT)
τοῦ ὁρισθέντος υἱοῦ θεοῦ ἐν δυνάμει κατὰ πνεῦμα ἁγιωσύνης ἐξ ἀναστάσεως νεκρῶν, Ἰησοῦ Χριστοῦ τοῦ κυρίου ἡμῶν,

Haydock's commentary

Who was predestined2 the Son of God. The learned bishop of Meaux, Bossuet, in his second Pastoral Instruction, in which he condemned the French translation of Mons. Simon, (p. 127.) takes notice, that according to St. Paul, and the constant doctrine of St. Augustine and St. Thomas Aquinas, Christ as man, or the human nature of Christ united to his divine person, was predestinated without any precedent merits, by a free and liberal predestination of God's goodness. (Witham)

Christ, as man, was predestinated to be the Son of God; and declared to be so (as the apostle here signifies) first by power, that is, by his working stupendous miracles; secondly, by the spirit of sanctification, that is, by his infinite sanctity; thirdly, by his resurrection, or raising himself from the dead. (Challoner)

2 Qui prædestinatus est. St. Chrysostom, om. a. p. 7. Ed. Sau. ti oun estin oristhentos; deichthentos, apophanthentos.

From Haydock's Catholic Bible Commentary, 1859, in the transcription made by Todd Easton and kept online by John Paul Wohlschied at johnblood.gitlab.io/haydock.

The Fathers on this verse

St Irenaeus Against Heresies: Book III, Chapter XVI. Proofs from the

3. Paul, when writing to the Romans, has explained this very point: “Paul, an apostle of Jesus Christ, predestinated unto the Gospel of God, which He had promised by His prophets in the holy Scriptures, concerning His Son, who was made to Him of the seed of David according to the flesh, who was predestinated the Son of God with power through the Spirit of holiness, by the resurrection from the dead of our Lord Jesus Christ.” And again, writing to the Romans about Israel, he says: “Whose are the fathers, and from whom is Christ according to the flesh, who is God over all, blessed for ever.” And again, in his Epistle to the Galatians, he says: “But when the fulness of time had come, God sent forth His Son, made of a woman, made under the law, to redeem them that were under the law, that we might receive the adoption;” plainly indicating one God, who did by the prophets make promise of the …

St Irenaeus Against Heresies: Book III, Chapter XXII. Christ assumed actual

1. Those, therefore, who allege that He took nothing from the Virgin do greatly err, [since,] in order that they may cast away the inheritance of the flesh, they also reject the analogy [between Him and Adam]. For if the one [who sprang] from the earth had indeed formation and substance from both the hand and workmanship of God, but the other not from the hand and workmanship of God, then He who was made after the image and likeness of the former did not, in that case, preserve the analogy of man, and He must seem an inconsistent piece of work, not having wherewith He may show His wisdom. But this is to say, that He also appeared putatively as man when He was not man, and that He was made man while taking nothing from man. …

Tertullian Against Praxeas, The Distinction of the Father and the Son, Thus Established, He Now Proves the Distinction of the Two Natures, Which Were, Without Confusion, United in the Person of the Son. The Subterfuges of Praxeas Thus Exposed

But why should I linger over matters which are so evident, when I ought to be attacking points on which they seek to obscure the plainest proof? For, confuted on all sides on the distinction between the Father and the Son, which we maintain without destroying their inseparable union, as (by the examples) of the sun and the ray, and the fountain and the river, yet, by help of (their conceit) an indivisible number, (with issues) of two and three, they endeavour to interpret this distinction in a way which shall nevertheless tally with their own opinions: so that, all in one Person, they distinguish two, Father and Son, understanding the Son to be flesh, that is man, that is Jesus; and the Father to be spirit, that is God, that is Christ. Thus they, while contending that the Father and the Son are one and the same, do in fact begin by dividing them rather than uniting them. …

Origen Origen De Principiis, Chapter IV

2. It would be tedious to collect out of all the passages in the Gospels the proofs by which the God of the law and of the Gospels is shown to be one and the same. Let us touch briefly upon the Acts of the Apostles, where Stephen and the other apostles address their prayers to that God who made heaven and earth, and who spoke by the mouth of His holy prophets, calling Him the “God of Abraham, of Isaac, and of Jacob;” the God who “brought forth His people out of the land of Egypt.” Which expressions undoubtedly clearly direct our understandings to faith in the Creator, and implant an affection for Him in those who have learned piously and faithfully thus to think of Him; according to the words of the Saviour Himself, who, when He was asked which was the greatest commandment in the law, replied, “Thou shalt love the Lord thy God with all thy heart, and with all thy soul, and with all thy m …

Origen Origen's Commentary on the Gospel of John, Chapter VI

“ All things were made through Him. ” The “through whom” is never found in the first place but always in the second, as in the Epistle to the Romans, “Paul a servant of Christ Jesus, a called Apostle, separated to the Gospel of God which He promised before by His prophets in Holy Scriptures, concerning His Son, who was born of the seed of David according to the flesh, determined the Son of God in power according to the Spirit of holiness, by the resurrection of the dead, Jesus Christ our Lord, through whom we received grace and apostleship, for obedience of the faith among all the nations, for His name’s sake.” For God promised aforehand by the prophets His own Gospel, the prophets being His ministers, and having their word to speak about Him “through whom.” And again God gave grace and apostleship to Paul and to the others for the obedience of the faith among all the nations, and this H …

Origen Origen's Commentary on Matthew, Chapter XVII

Now bring together from the Gospels those who call Him Son of David, as she, and the blind men in Jericho; and who call Him Son of God, and that without the addition “truly” like the demoniacs who say, “What have we to do with Thee, Thou Son of God;” and who call Him so with the addition “truly,” like those in the boat who worshipped Him saying, “Truly Thou art the Son of God.” For the bringing together of these passages will, I think, be useful to you with a view to seeing the difference of those who come (to Jesus); some indeed come as to Him “who was born of the seed of David according to the flesh;” but others come to Him who “was declared to be the Son of God with power, according to the spirit of holiness;” and of these some with the “truly,” and some without it. …

St Augustine On the Holy Trinity, Why This Opinion is to Be Rejected

7. For such expressions are customary in the Scriptures; and yet some persons, while maintaining the Catholic faith, do not carefully attend to them, in such wise that they think the words, “God made man in the image of God,” to mean that the Father made man after the image of the Son; and they thus desire to assert that the Son also is called God in the divine Scriptures, as if there were not other most true and clear proofs wherein the Son is called not only God, but also the true God. For whilst they aim at explaining another difficulty in this text, they become so entangled that they cannot extricate themselves. For if the Father made man after the image of the Son, so that he is not the image of the Father, but of the Son, then the Son is unlike the Father. …

St Augustine Acts or Disputation Against Fortunatus the Manichæan, Disputation of the First Day

19. Augustin said: That we should discuss on rational grounds the belief in two natures, has been made obligatory by those who are hearing us. But inasmuch as you have again betaken yourself to the Scriptures, I descend to them, and demand that nothing be passed by, lest using certain statements we should bring confusion into the minds of those to whom the Scriptures are not well known. Let us therefore consider a statement that the apostle has in his epistle to the Romans. For on the first page is what is strongly against you. …

St Augustine Expositions on the Book of Psalms, Psalm LXVIII

12. “The Lord shall give the Word” ( ver. 11 ): to wit, food for His animals which shall dwell therein. But what shall these animals work to whom He shall give the word? What but that which followeth? “To them preaching the Gospel in much virtue.” With what virtue, but with that strength wherein He leadeth forth men fettered? Perchance also here he speaketh of that virtue, wherewith in preaching the Gospel they wrought wondrous signs. Who then “shall give the Word to men preaching the Gospel with much virtue”? “The King,” he saith, “of the virtues of the Beloved” ( ver. 12 ). The Father therefore is King of the virtues of the Son. For the Beloved, when there is not specified any person that is beloved, by a substitution of name, of the Only Son is understood. …

St John Chrysostom The Homilies of St. John Chrysostom on Paul's Epistle to the Romans, Homily I on Rom. i. 1, 2

Ver. 4 . “And declared to be the Son of God with power, according to the Spirit of Holiness, by the resurrection from the dead, even Jesus Christ.”

St John Chrysostom The Homilies of St. John Chrysostom on Paul's Epistle to the Romans, Homily XVII on Rom. x. 1

“If thou confess with thy mouth the Lord Jesus, and believe in thy heart that God hath raised Him from the dead, thou shalt be saved.” Then again that we may not seem to be making it contemptible by showing it to be easy and cheap, observe how he expands his account of it. For he does not come immediately to the words just given, but what does he say? “But the righteousness which is of faith saith on this wise; Say not in thine heart, Who shall go up into heaven? (that is, to bring Christ down); or, Who shall descend into the deep? (that is, to bring up Christ again from the dead.”) For as to the virtue manifested in works there is opposed a listlessness, which relaxeth our labors, and it requireth a very wakeful soul not to yield to it: thus, when one is required to believe, there are reasonings which confuse and make havoc of the minds of most men, and it wants a soul of some vigor to …

St John Chrysostom The Homilies of St. John Chrysostom on the Gospel of St. John, John 2.11

[3.] Wherefore then did He not resolve the difficulty and say, “I speak not of that Temple, but of My flesh”? Why does the Evangelist, writing the Gospel at a later period, interpret the saying, and Jesus keep silence at the time? Why did He so keep silence? Because they would not have received His word; for if not even the disciples were able to understand the saying, much less were the multitudes. “When,” saith the Evangelist, “He was risen from the dead, then they remembered, and believed the Scripture and His word.” There were two things that hindered them for the time, one the fact of the Resurrection, the other, the greater question whether He was God that dwelt within; of both which things He spake darkly when He said, “Destroy this Temple, and I will rear it up in three days.” And this St. …

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The Catechism cites this verse