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Ecclesiasticus 40:1

Great labour is created for all men, and a heavy yoke is upon the children of Adam, from the day of their coming out of their mother's womb, until the day of their burial into the mother of all.

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The verse in its languages

Vulgate (Clementine)
Occupatio magna creata est omnibus hominibus, et jugum grave super filios Adam, a die exitus de ventre matris eorum usque in diem sepulturæ in matrem omnium.
Septuagint (Swete)
Verse numbering differs here, so nothing is shown rather than the wrong verse.

Haydock's commentary

Labour, "anxiety," ascholia. (Menochius)

All misery (Calmet) is in consequence of original sin. (Worthington)

The life of man is a trial, Job vii. 1., and xiv. 1.

Of all. The earth, (Calmet) which covers us, when all other things cast us away. (Pliny, [Natural History?] ii. 63.)

From Haydock's Catholic Bible Commentary, 1859, in the transcription made by Todd Easton and kept online by John Paul Wohlschied at johnblood.gitlab.io/haydock.

The Fathers on this verse

St Augustine City of God, Of the Temporary Punishments of This Life to Which the Human Condition is Subject

Quite exceptional are those who are not punished in this life, but only afterwards. Yet that there have been some who have reached the decrepitude of age without experiencing even the slightest sickness, and who have had uninterrupted enjoyment of life, I know both from report and from my own observation. However, the very life we mortals lead is itself all punishment, for it is all temptation, as the Scriptures declare, where it is written, “Is not the life of man upon earth a temptation?” For ignorance is itself no slight punishment, or want of culture, which it is with justice thought so necessary to escape, that boys are compelled, under pain of severe punishment, to learn trades or letters; and the learning to which they are driven by punishment is itself so much of a punishment to them, that they sometimes prefer the pain that drives them to the pain to which they are driven by it. …

St Augustine The Enchiridion, The Pardon of Sin Has Reference Chiefly to the Future Judgment

Now the pardon of sin has reference chiefly to the future judgment. For, as far as this life is concerned, the saying of Scripture holds good: “A heavy yoke is upon the sons of Adam, from the day that they go out of their mother’s womb, till the day that they return to the mother of all things.” So that we see even infants, after baptism and regeneration, suffering from the infliction of divers evils: and thus we are given to understand, that all that is set forth in the sacraments of salvation refers rather to the hope of future good, than to the retaining or attaining of present blessings. …

St Augustine On Marriage and Concupiscence, The Rise and Origin of Evil. The Exorcism and Exsufflation of Infants, a Primitive Christian Rite

As to the passage, which he seemed to himself to indite in a pious vein, as it were, “If nature is of God, there cannot be original sin in it,” would not another person seem even to him to give a still more pious turn to it, thus: “If nature is of God, there cannot arise any sin in it?” And yet this is not true. The Manicheans, indeed, meant to assert this, and they endeavoured to steep in all sorts of evil the very nature of God itself, and not His creature, made out of nothing. For evil arose in nothing else than what was good, not, however, the supreme and unchangeable good which is God’s nature, but that which was made out of nothing by the wisdom of God. This, then, is the reason why man is claimed for a divine work; for he would not be man unless he were made by the operation of God. …

St Augustine Expositions on the Book of Psalms, Gimel

18. Here an important question ariseth respecting the soul. For the words, I am a sojourner, or lodger, or stranger upon earth, cannot seem to have been said in reference to the body, since the body derives its origin from the earth. But in this most profound question I dare not define anything. For if it might justly have been said in respect of the soul (which God forbid we should suppose derived from the earth), “I am a lodger,” or “stranger upon earth;” or in reference to the whole man, since he was at one time an inhabitant of Paradise, where he who spake these words was not; or, what is more free from all controversy, if it be not every man who could say this, but one to whom an everlasting country hath been promised in heaven: this I know, “that the life of man on earth is a temptation;” and that “there is a heavy yoke upon the sons of Adam.” But it pleaseth me more to discuss the …