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Ephesians 5:31

For this cause shall a man leave his father and mother, and shall cleave to his wife, and they shall be two in one flesh.

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The verse in its languages

Vulgate (Clementine)
Propter hoc relinquet homo patrem et matrem suam, et adhærebit uxori suæ, et erunt duo in carne una.
Greek New Testament (SBLGNT)
ἀντὶ τούτου καταλείψει ἄνθρωπος τὸν πατέρα καὶ τὴν μητέρα καὶ προσκολληθήσεται τῇ γυναικὶ αὐτοῦ, καὶ ἔσονται οἱ δύο εἰς σάρκα μίαν.

Haydock's commentary

On verses 28 to 31

He that loveth his wife, loveth himself. St. Paul would have this a love like that which a man hath for himself, or for his own flesh, when they are now joined in wedlock, and are become as it were one flesh and one person, as to a civil life and society. See Matthew xix. 5. The wife is to be considered as a part of the husband, as a member of his body, of his flesh, and of his bones. The words are to be taken with an allusion to what Adam said, (Genesis ii. 23.) This is now bone of my bones, &c. And so, according to the apostle, speaking figuratively, the Church, which is the spouse of Christ, is framed as it were of his bones and of his flesh sacrificed on the cross. (Witham)

From Haydock's Catholic Bible Commentary, 1859, in the transcription made by Todd Easton and kept online by John Paul Wohlschied at johnblood.gitlab.io/haydock.

The Fathers on this verse

Tertullian A Treatise on the Soul, Spirit--A Term Expressive of an Operation of the Soul, Not of Its Nature. To Be Carefully Distinguished from the Spirit of God

But the nature of my present inquiry obliges me to call the soul spirit or breath, because to breathe is ascribed to another substance. We, however, claim this (operation) for the soul, which we acknowledge to be an indivisible simple substance, and therefore we must call it spirit in a definitive sense, not because of its condition, but of its action; not in respect of its nature, but of its operation; because it respires , and not because it is spirit in any especial sense. For to blow or breathe is to respire. So that we are driven to describe, by (the term which indicates this respiration, that is to say) spirit, the soul which we hold to be, by the propriety of its action, breath. Moreover, we properly and especially insist on calling it breath (or spirit), in opposition to Hermogenes, who derives the soul from matter instead of from the afflatus or breath of God. …

Tertullian The Five Books Against Marcion, Sundry Features of the Prophetic Style: Principles of Its Interpretation

These preliminary remarks I have ventured to make at this first step of the discussion and while the conflict is, as it were, from a distance. But inasmuch as I shall now from this point have to grapple with my opponent on a distinct issue and in close combat, I perceive that I must advance even here some lines, at which the battle will have to be delivered; they are the Scriptures of the Creator. For as I shall have to prove that Christ was from the Creator, according to these (Scriptures), which were afterwards accomplished in the Creator’s Christ, I find it necessary to set forth the form and, so to speak, the nature of the Scriptures themselves, that they may not distract the reader’s attention by being called into controversy at the moment of their application to subjects of discussion, and by their proof being confounded with the proof of the subjects themselves. …

Tertullian The Five Books Against Marcion, Another Foolish Erasure of Marcion's Exposed. Certain Figurative Expressions of the Apostle, Suggested by the Language of the Old Testament. Collation of Many Passages of This Epistle, with Precepts and Statements in the Pentateuch, the Psalms, and the Prophets. All Alike Teach Us the Will and Purpose of the Creator

As our heretic is so fond of his pruning-knife, I do not wonder when syllables are expunged by his hand, seeing that entire pages are usually the matter on which he practises his effacing process. The apostle declares that to himself, “less than the least of all saints, was the grace given” of enlightening all men as to “what was the fellowship of the mystery, which during the ages had been hid in God, who created all things.” The heretic erased the preposition in , and made the clause run thus: (“what is the fellowship of the mystery) which hath for ages been hidden from the God who created all things.” The falsification, however, is flagrantly absurd. …

Tertullian To His Wife, Chapter VIII

What am I to fasten on as the cause of this madness, except the weakness of faith, ever prone to the concupiscences of worldly joys? which, indeed, is chiefly found among the wealthier; for the more any is rich, and inflated with the name of “matron,” the more capacious house does she require for her burdens, as it were a field wherein ambition may run its course. To such the churches look paltry. A rich man is a difficult thing (to find) in the house of God; and if such an one is (found there), difficult (is it to find such) unmarried. What, then, are they to do? Whence but from the devil are they to seek a husband apt for maintaining their sedan, and their mules, and their hair-curlers of outlandish stature? A Christian, even although rich, would perhaps not afford (all) these. Set before yourself, I beg of you, the examples of Gentiles. …

Tertullian On Exhortation to Chastity, Chapter V

For the laying down of the law of once marrying, the very origin of the human race is our authority; witnessing as it emphatically does what God constituted in the beginning for a type to be examined with care by posterity. For when He had moulded man, and had foreseen that a peer was necessary for him, He borrowed from his ribs one, and fashioned for him one woman; whereas, of course, neither the Artificer nor the material would have been insufficient (for the creation of more). There were more ribs in Adam, and hands that knew no weariness in God; but not more wives in the eye of God. And accordingly the man of God, Adam, and the woman of God, Eve, discharging mutually (the duties of) one marriage, sanctioned for mankind a type by (the considerations of) the authoritative precedent of their origin and the primal will of God. …

St Cyprian The Epistles of Cyprian, Epistle XLVIII

1. Cyprian to Cornelius his brother, greeting. You have acted, dearest brother, both with diligence and love, in sending us in haste Nicephorus the acolyte, who both told us the glorious gladness concerning the return of the confessors, and most fully instructed us against the new and mischievous devices of Novatian and Novatus for attacking the Church of Christ. For whereas on the day before, that mischievous faction of heretical wickedness had arrived here, itself already lost and ready to ruin others who should join it, on the day after, Nicephorus arrived with your letter. …

St Methodius The Banquet of the Ten Virgins; or Concerning Chastity, Chapter I

Chapter I. Passages of Holy Scripture Compared.

St Methodius The Banquet of the Ten Virgins; or Concerning Chastity, Chapter VIII

For man, having been composed, like water, of wisdom and life, has become identical with the very same untainted light which poured into him. Whence it was that the apostle directly referred to Christ the words which had been spoken of Adam. For thus will it be most certainly agreed that the Church is formed out of His bones and flesh; and it was for this cause that the Word, leaving His Father in heaven, came down to be “joined to His wife;” and slept in the trance of His passion, and willingly suffered death for her, that He might present the Church to Himself glorious and blameless, having cleansed her by the laver, for the receiving of the spiritual and blessed seed, which is sown by Him who with whispers implants it in the depths of the mind; and is conceived and formed by the Church, as by a woman. so as to give birth and nourishment to virtue. …

Origen Origen's Commentary on Matthew, Chapter XVII

But since the Apostle understands the words, “ And they twain shall be one flesh, ” of Christ and the church, we must say that Christ keeping the saying, “What God hath joined together let not man put asunder,” did not put away His former wife, so to speak, that is, the former synagogue, for any other cause than that that wife committed fornication, being made an adulteress by the evil one, and along with him plotted against her husband and slew Him, saying, “Away with such a fellow from the earth, crucify Him, crucify Him.” It was she therefore who herself revolted, rather than her husband who put her away and dismissed her; wherefore, reproaching her for falling away from him, it says in Isaiah, “Of what kind is the bill of your mother’s divorcement, with which I sent her away?” And He who at the beginning created Him “who is in the form of God” after the image, made Him male, and the …

St Augustine Reply to Faustus the Manichæan, Faustus denies that the prophets predicted Christ. Augustin proves such prediction from the New Testament, and expounds at length the principal types of Christ in the Old Testament

8. In the creation God finished His works in six days, and rested on the seventh. The history of the world contains six periods marked by the dealings of God with men. The first period is from Adam to Noah; the second, from Noah to Abraham; the third, from Abraham to David; the fourth, from David to the captivity in Babylon; the fifth, from the captivity to the advent of lowliness of our Lord Jesus Christ; the sixth is now in progress, and will end in the coming of the exalted Saviour to judgment. What answers to the seventh day is the rest of the saints, not in this life, but in another, where the rich man saw Lazarus at rest while he was tormented in hell; where there is no evening, because there is no decay. …

St Augustine Reply to Faustus the Manichæan, Faustus states his objections to the morality of the law and the prophets, and Augustin seeks by the application of the type and the allegory to explain away the moral difficulties of the Old Testament

38. But a pleasure which all must feel is obtained from this narrative so faithfully recorded in the Holy Scriptures, when we examine into the prophetic character of the action, and knock with pious faith and diligence at the door of the mystery, that the Lord may open, and show us who was prefigured in the ancient personage, and whose wife this is, who, while in a foreign land and among strangers, is not allowed to be stained or defiled, that she may be brought to her own husband without spot or wrinkle. Thus we find that the righteous life of the Church is for the glory of Christ, that her beauty may bring honor to her husband, as Abraham was honored on account of the beauty of Sara among the inhabitants of that foreign land. …

St Augustine Our Lord’s Sermon on the Mount, Chapter XII

42. It is usual, therefore, to ask what He means, when He says: “But ye, when ye fast, anoint your head, and wash your faces, that ye appear not unto men to fast.” For it would not be right in any one to teach (although we may wash our face according to daily custom) that we ought also to have our heads anointed when we fast. If, then, all admit this to be most unseemly, we must understand this precept with respect to anointing the head and washing the face as referring to the inner man. Hence, to anoint the head refers to joy; to wash the face, on the other hand, refers to purity: and therefore that man anoints his head who rejoices inwardly in his mind and reason. For we rightly understand that as being the head which has the pre-eminence in the soul, and by which it is evident that the other parts of man are ruled and governed. …

12 more passages of the Fathers cite this verse. The Motif Searcher in the palace lists them all.

The Catechism cites this verse