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Ephesians 6:18

By all prayer and supplication praying at all times in the spirit; and in the same watching with all instance and supplication for all the saints:

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The verse in its languages

Vulgate (Clementine)
per omnem orationem et obsecrationem orantes omni tempore in spiritu : et in ipso vigilantes in omni instantia et obsecratione pro omnibus sanctis :
Greek New Testament (SBLGNT)
διὰ πάσης προσευχῆς καὶ δεήσεως, προσευχόμενοι ἐν παντὶ καιρῷ ἐν πνεύματι, καὶ εἰς αὐτὸ ἀγρυπνοῦντες ἐν πάσῃ προσκαρτερήσει καὶ δεήσει περὶ πάντων τῶν ἁγίων,

The Fathers on this verse

Tertullian On Prayer, Of Kneeling

In the matter of kneeling also prayer is subject to diversity of observance, through the act of some few who abstain from kneeling on the Sabbath; and since this dissension is particularly on its trial before the churches, the Lord will give His grace that the dissentients may either yield, or else indulge their opinion without offence to others. We, however (just as we have received), only on the day of the Lord’s Resurrection ought to guard not only against kneeling, but every posture and office of solicitude; deferring even our businesses lest we give any place to the devil. Similarly, too, in the period of Pentecost; which period we distinguish by the same solemnity of exultation. …

Tertullian On Prayer, Of the Spiritual Victim, Which Prayer is

For this is the spiritual victim which has abolished the pristine sacrifices. “To what purpose,” saith He, “(bring ye) me the multitude of your sacrifices? I am full of holocausts of rams, and I desire not the fat of rams, and the blood of bulls and of goats. For who hath required these from your hands?” What, then, God has required the Gospel teaches. “An hour will come,” saith He, “when the true adorers shall adore the Father in spirit and truth. …

St John Chrysostom The Commentary and Homilies of St. John Chrysostom on Galatians and Ephesians, Ephesians 6:14-17

Ver. 18, 19, 20 . “With all prayer and supplication,” saith he, “praying at all seasons in the Spirit, and watching thereunto in all perseverance and supplication for all the saints; and on my behalf that utterance may be given unto me, in opening my mouth to make known with boldness the mystery of the gospel, for which I am an ambassador in chains, that in it I may speak boldly, as I ought to speak.”

St John Chrysostom The Homilies of St. John Chrysostom on the Epistle to the Hebrews, Hebrews 4.11-13

[11.] What then are these things to us (one says) who are not monastics? Sayest thou this to me? Say it to Paul, when he says, “Watching with all perseverance and supplication” ( Eph. vi. 18 ), when he says, “Make not provision for the flesh, to fulfill the lusts thereof.” ( Rom. xiii. 14 .) For surely he wrote not these things to solitaries only, but to all that are in cities. For ought the man who lives in the world to have any advantage over the solitary, save only the living with a wife? In this point he has allowance, but in others none, but it is his duty to do all things equally with the solitary.

St Cyril of Jerusalem Continuation of the Discourse on the Holy Ghost

33. And that the Holy Ghost subsists, and lives, and speaks, and foretells, I have often said in what goes before, and Paul writes it plainly to Timothy: Now the Spirit speaketh expressly, that in later times some shall depart from the faith , which we see in the divisions not only of former times but also of our own; so motley and diversified are the errors of the heretics. And again the same Paul says, Which in other generations was not made known unto the sons of men, as it hath now been revealed unto His Holy Apostles and Prophets in the Spirit . And again, Wherefore, as saith the Holy Ghost ; and again, The Holy Ghost also witnesseth to us . And again he calls unto the soldiers of righteousness, saying, And take the helmet of salvation, and the sword of the Spirit, which is the Word of God, with all prayer and supplication . …

The Catechism cites this verse