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Osee 4:6

My people have been silent, because they had no knowledge: because thou hast rejected knowledge, I will reject thee, that thou shalt not do the office of priesthood to me: and thou hast forgotten the law of thy God, I also will forget thy children.

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The verse in its languages

Vulgate (Clementine)
Conticuit populus meus, eo quod non habuerit scientiam : quia tu scientiam repulisti, repellam te, ne sacerdotio fungaris mihi ; et oblita es legis Dei tui, obliviscar filiorum tuorum et ego.
Septuagint (Swete)
ὡμοιώθη ὁ λαός μου ὡς οὐκ ἔχων γνῶσιν· ὅτι σὺ ἐπίγνωσιν ἀπώσω, κἀγὼ ἀπώσομαι σὲ τοῦ ἱερατεύειν μοι· καὶ ἐπελάθου νόμον θεοῦ σου, κἀγὼ ἐπιλήσομαι τέκνων σου.
Hebrew (WLC)
נִדְמ֥וּ עַמִּ֖י מִבְּלִ֣י הַדָּ֑עַת כִּֽי אַתָּ֞ה הַדַּ֣עַת מָאַ֗סְתָּ וְאֶמְאָֽסְאךָ֙ מִכַּהֵ֣ן לִ֔י וַתִּשְׁכַּח֙ תּוֹרַ֣ת אֱלֹהֶ֔יךָ אֶשְׁכַּ֥ח בָּנֶ֖יךָ גַּם אָֽנִי

Haydock's commentary

Silent. Septuagint, "like those who had," &c.

Knowledge. Jeroboam I had appointed unlawful priests, and some of the house of Aaron went over to him, and were excluded from officiating at Jerusalem, after the captivity, 1 Kings xii. 31., and Ezechiel xliv. 10. Knowledge is always expected of priests, Deuteronomy xvii. 8., and Malachias ii. 7. (Gratian. dist. 38. c. omnes.) (Calmet)

When the power of sacrificing is withdrawn, all spiritual functions cease, as sacrifice belongs properly to a priest. (Worthington)

From Haydock's Catholic Bible Commentary, 1859, in the transcription made by Todd Easton and kept online by John Paul Wohlschied at johnblood.gitlab.io/haydock.

The Fathers on this verse

St John Chrysostom The Homilies of St. John Chrysostom on the Gospel of St. John, John 12.34

Here again is another question, but it is not so if we rightly consider it. For as the sun dazzles the eyes of the weak, not by reason of its proper nature, so it is with those who give not heed to the words of God. Thus, in the case of Pharaoh, He is said to have hardened his heart, and so it is with those who are at all contentious against the words of God. This is a peculiar mode of speech in Scripture, as also the, “He gave them over unto a reprobate mind” ( Rom. i. 28 ), and the, “He divided them to the nations,” that is, allowed, permitted them to go. For the writer doth not here introduce God as Himself working these things, but showeth that they took place through the wickedness of others. For, when we are abandoned by God, we are given up to the devil, and when so given up, we suffer ten thousand dreadful things. …

St Gregory Nazianzen In Defence of His Flight to Pontus, and His Return, After His Ordination to the Priesthood, with an Exposition of the Character of the Priestly Office

113. Moreover, to distinguish still more clearly between them, we have, against the fear of office, a possible help in the law of obedience, inasmuch as God in His goodness rewards our faith, and makes a perfect ruler of the man who has confidence in Him, and places all his hopes in Him; but against the danger of disobedience I know of nothing which can help us, and of no ground to encourage our confidence. For it is to be feared that we shall have to hear these words concerning those who have been entrusted to us: I will require their souls at your hands; and, Because ye have rejected me, and not been leaders and rulers of my people, I also will reject you, that I should not be king over you; and, As ye refused to hearken to My voice, and turned a stubborn back, and were disobedient, so shall it be when ye call upon Me, and I will not regard nor give ear to your prayer. …

St Gregory Nazianzen The Last Farewell in the Presence of the One Hundred and Fifty Bishops

8. Thou countest tens of thousands, God counts those who are in a state of salvation; thou countest the dust which is without number, I the vessels of election. For nothing is so magnificent in God’s sight as pure doctrine, and a soul perfect in all the dogmas of the truth. For there is nothing worthy of Him Who made all things, of Him by Whom are all things, and for Whom are all things, so that it can be given or offered to God: not merely the handiwork or means of any individual, but even if we wished to honour Him, by uniting together all the property and handiwork of all mankind. …

St John Cassian The Conferences of John Cassian. Part II. Containing Conferences XI-XVII, Chapter XVI. The answer to the effect that bad men cannot possess true knowledge

Nesteros : One who does not carefully weigh every word of the opinions uttered cannot rightly discover the value of the assertion. For we said to begin with that men of this sort only possess skill in disputation and ornaments of speech; but cannot penetrate to the very heart of Scripture and the mysteries of its spiritual meanings. For true knowledge is only acquired by true worshippers of God; and certainly this people does not possess it to whom it is said: “Hear, O, foolish people, thou who hast no heart: ye who having eyes see not, and having ears, hear not.” And again: “Because thou hast rejected knowledge, I also will reject thee from acting as My priest.” For as it is said that in Christ “all the treasures of wisdom and knowledge are hid,” how can we hold that he who has scorned to find Christ, or, when He is found blasphemes Him with impious lips, or at least defiles the Catholi …