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Isaias 41:4

Who hath wrought and done these things, calling the generations from the beginning? I the Lord, I am the first and the last.

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The verse in its languages

Vulgate (Clementine)
Quis hæc operatus est, et fecit, vocans generationes ab exordio ? Ego Dominus : primus et novissimus ego sum.
Septuagint (Swete)
τίς ἐνήργησεν καὶ ἐποίησεν ταῦτα; ἐκάλεσεν αὐτὴν ὁ καλῶν αὐτὴν ἀπὸ γενεῶν ἀρχῆς· ἐγὼ θεὸς πρῶτος, καὶ εἰς τὰ ἐπερχόμενα ἐγώ εἰμι.
Hebrew (WLC)
מִֽי פָעַ֣ל וְעָשָׂ֔ה קֹרֵ֥א הַדֹּר֖וֹת מֵרֹ֑אשׁ אֲנִ֤י יְהוָה֙ רִאשׁ֔וֹן וְאֶת אַחֲרֹנִ֖ים אֲנִי הֽוּא

Haydock's commentary

Beginning. Disposing all things, as the conquests of Cyrus, announced so long before by name, evince.

Last. Alpha and Omega, Apocalypse i. 8., and xxii. 13.

From Haydock's Catholic Bible Commentary, 1859, in the transcription made by Todd Easton and kept online by John Paul Wohlschied at johnblood.gitlab.io/haydock.

The Fathers on this verse

Tertullian Against Hermogenes, The Shifts to Which Hermogenes is Reduced, Who Deifies Matter, and Yet is Unwilling to Hold Him Equal with the Divine Creator

He declares that God’s attribute is still safe to Him, of being the only God, and the First, and the Author of all things, and the Lord of all things, and being incomparable to any, qualities which he straightway ascribes to Matter also. He is God, to be sure. God shall also attest the same; but He has also sworn sometimes by Himself, that there is no other God like Him. Hermogenes, however, will make Him a liar. For Matter will be such a God as He, being unmade, unborn, without beginning, and without end. God will say, “I am the first!” Yet how is He the first, when Matter is co-eternal with Him? Between co-eternals and contemporaries there is no sequence of rank. Is then, Matter also the first? “I,” says the Lord, “have stretched out the heavens alone.” But indeed He was not alone, when that likewise stretched them out, of which He made the expanse. …

St Gregory Nazianzen The Third Theological Oration. On the Son

XVII. For we have learnt to believe in and to teach the Deity of the Son from their great and lofty utterances. And what utterances are these? These: God, The Word, He That Was In The Beginning and With The Beginning, and The Beginning. “In the Beginning was The Word, and the Word was with God, and the Word was God,” and “With Thee is the Beginning,” and “He who calleth her The Beginning from generations.” Then the Son is Only-begotten: The only “begotten Son which is in the bosom of the Father, it says, He hath declared Him.” The Way, the Truth, the Life, the Light. …

St Gregory Nazianzen The Fifth Theological Oration. On the Holy Spirit

XXIII. Again, where do you get your Unbegotten and Unoriginate, those two citadels of your position, or we our Immortal? Show me these in so many words, or we shall either set them aside, or erase them as not contained in Scripture; and you are slain by your own principle, the names you rely on being overthrown, and therewith the wall of refuge in which you trusted. Is it not evident that they are due to passages which imply them, though the words do not actually occur? What are these passages? I am the first, and I am the last, and before Me there was no God, neither shall there be after Me. For all that depends on that Am makes for my side, for it has neither beginning nor ending. When you accept this, that nothing is before Him, and that He has not an older Cause, you have implicitly given Him the titles Unbegotten and Unoriginate. …

St Ambrose Exposition of the Christian Faith, Chapter IX. Various quibbling arguments, advanced by the Arians to show that the Son had a beginning of existence, are considered and refuted, on the ground that whilst the Arians plainly prove nothing, or if they prove anything, prove it against themselves, (inasmuch as He Who is the beginning of all cannot Himself have a beginning), their reasonings do not even hold true with regard to facts of human existence. Time could not be before He was, Who is the Author of time--if indeed at some time He was not in existence, then the Father was without His Power and Wisdom. Again, our own human experience shows that a person is said to exist before he is born

108. But neither had the Son of God any beginning, seeing that He already was at the beginning, nor shall He come to an end, Who is the Beginning and the End of the Universe; for being the Beginning, how could He take and receive that which He already had, or how shall He come to an end, being Himself the End of all things, so that in that End we have an abiding-place without end? The Divine Generation is not an event occurring in the course of time, and within its limits, and therefore before it time is not, and in it time has no place.